120796-97-6

Basic information

• Product Name: BIG ET-1 (1-38) (HUMAN)
• Synonyms: BIG ENDOTHELIN-1 (1-38) (HUMAN);BIG ENDOTHELIN-1 (HUMAN);BIG-ENDOTHELIN-I (1-38), HUMAN;BIG ET-1 (1-38) (HUMAN);BIG ENDOTHELIN-1 (HUMAN, 1-38);BIG ENDOTHELIN 38 HUMAN;CYS-SER-CYS-SER-SER-LEU-MET-ASP-LYS-GLU-CYS-VAL-TYR-PHE-CYS-HIS-LEU-ASP-ILE-ILE-TRP-VAL-ASN-THR-PRO-GLU-HIS-VAL-VAL-PRO-TYR-GLY-LEU-GLY-SER-PRO-ARG-SER;CSCSSLMDKECVYFCHLDIIWVNTPEHVVPYGLGSPRS
• CAS NO: 120796-97-6
• Molecular Formula: C189H282N48O56S5
• Molecular Weight: 4282.87
• Mol File: 120796-97-6.mol
• Article Data: 0

Chemical Properties

• Appearance: /
• Storage Temp.: −20°C
• CAS DataBase Reference: BIG ET-1 (1-38) (HUMAN)(CAS DataBase Reference)
• NIST Chemistry Reference: BIG ET-1 (1-38) (HUMAN)(120796-97-6)
• EPA Substance Registry System: BIG ET-1 (1-38) (HUMAN)(120796-97-6)

Safety Data

• WGK Germany: 3
• Hazardous Substances Data: 120796-97-6(Hazardous Substances Data)

Usage

General Description

BIG ET-1 (1-38) (HUMAN) is a peptide hormone composed of 38 amino acids that functions as a vasoconstrictor. It is a precursor to endothelin-1 (ET-1), which is involved in the regulation of blood pressure and vascular tone. ET-1 is also known to play a role in the pathophysiology of various cardiovascular diseases, including hypertension, heart failure, and atherosclerosis. The conversion of big ET-1 to its active form, ET-1, is regulated by the enzyme endothelin-converting enzyme-1 (ECE-1). Research on the regulation and function of big ET-1 (1-38) (HUMAN) has focused on its potential as a therapeutic target for cardiovascular disorders and as a biomarker for disease progression.