1207966-13-9

Upstream product

• 1070781-97-3 (2E)-3-(2,4-dimethoxyphenyl)-1-[2-methoxy-4,6-bis(2-propenyloxy)phenyl]-2-propen-1-one 
• 3602-54-8 4,6-dihydroxy-2-methoxyacetophenone 
• 613-45-6 2,4-Dimethoxybenzaldehyde 

Relevant academic research and scientific papers

In vitro and in vivo anti-Leishmania activity of polysubstituted synthetic chalcones

The in vitro screening of 43 polysubstituted chalcones against Leishmania amazonensis axenic amastigotes, led to the evaluation of 9 of them in a macrophage-infected model with the two other most infectious Leishmania species prevalent in Peru (L. braziliensis and L. peruviana). The five most active and selective chalcones were studied in vivo, resulting on the identification of two chalcones with high reduction parasite burden percentages.

13C Nuclear Magnetic Resonance Studies on 1,3-Diphenylprop-2-enones

The 13C NMR spectra of 48 differently substituted chalcones (1,3-diphenylprop-2-enones) have been recorded and the results are discussed.The data will be useful in the identification of new/natural chalcones.