1207970-72-6

Upstream product

• 1423-26-3 (meta-(trifluoromethyl)phenyl)boronic acid 
• 1171926-64-9 (7-bromo-1-benzothiophen-2-yl)methanol 

Downstream Products

• 1313195-95-7 1-(2-(3-(trifluoromethyl)benzyl)benzo[b]thiophen-7-yl)-1H-pyrazole-4-carboxylic acid 
• 1313196-35-8 3,5-dimethyl-1-[2-[3-(trifluoromethyl)benzyl]-1-benzothiophen-7-yl]-1H-pyrazole-4-carboxylic acid 
• 1313196-06-3 3-methyl-1-[2-[3-(trifluoromethyl)benzyl]-1-benzothiophen-7-yl]-1H-pyrazole-4-carboylic acid 
• 1313196-05-2 5-methyl-1-[2-[3-(trifluoromethyl)benzyl]-1-benzothiophen-7-yl]-1H-pyrazole-4-carboxylic acid 
• 1313196-44-9 ethyl 5-(hydroxymethyl)-3-methyl-1-[2-[3-(trifluoromethyl)benzyl]-1-benzothiophen-7-yl]-1H-pyrazole-4-carboxylate 
• 1313196-45-0 5-(hydroxymethyl)-3-methyl-1-[2-[3-(trifluoromethyl)benzyl]-1-benzothiophen-7-yl]-1H-pyrazole-4-carboxylic acid 
• 1313196-77-8 1-methyl-3-{2-[3-(trifluoromethyl)benzyl]-1-benzothiophen-7-yl}-1H-pyrazole-5-carboxylic acid 
• 1313197-98-6 N-(2-hydroxyethyl)-1-methyl-3-(2-(3-(trifluoromethyl)benzyl)-1-benzothiophen-7-yl)-1H-pyrazole-5-carboxamide 
• 1313195-94-6 ethyl 1-(2-(3-(trifluoromethyl)benzyl)-1-benzothiophen-7-yl)-1H-pyrazole-4-carboxylate 
• 1313196-34-7 ethyl 3,5-dimethyl-1-(2-(3-(trifluoromethyl)benzyl)-1-benzothiophen-7-yl)-1H-pyrazole-4-carboxylate 
• 1313196-83-6 N-(2-methoxyethyl)-1-(2-(3-(trifluoromethyl)benzyl)-1-benzothiophen-7-yl)-1H-pyrazole-4-carboxamide 
• 1313197-33-9 N-(2-methoxyethyl)-3,5-dimethyl-1-(2-(3-(trifluoromethyl)benzyl)-1-benzothiophen-7-yl)-1H-pyrazole-4-carboxamide 
• 1313196-82-5 N-(2-hydroxyethyl)-1-(2-(3-(trifluoromethyl)benzyl)-1-benzothiophen-7-yl)-1H-pyrazole-4-carboxamide 
• 1313197-34-0 N-(2-hydroxyethyl)-3,5-dimethyl-1-(2-(3-(trifluoromethyl)benzyl)-1-benzothiophen-7-yl)-1H-pyrazole-4-carboxamide 

Relevant academic research and scientific papers

Design and synthesis of 1-(1-benzothiophen-7-yl)-1H-pyrazole, a novel series of G protein-coupled receptor 52 (GPR52) agonists

G-protein-coupled receptor 52 (GPR52) is classified as an orphan Gs-coupled G-protein-coupled receptor. GPR52 cancels dopamine D2 receptor signaling and activates dopamine D1/N-methyl-D-aspartate receptors via intracellular cAMP accumulation. Therefore, G