1208000-33-2Relevant academic research and scientific papers
Structure-based design, synthesis and biological evaluation of new N-carboxyphenylpyrrole derivatives as HIV fusion inhibitors targeting gp41
Wang, Yong,Lu, Hong,Zhu, Qiang,Jiang, Shibo,Liao, Yun
scheme or table, p. 189 - 192 (2010/04/02)
A new series of N-carboxyphenylpyrrole ligands were designed using GeometryFit based on an X-ray crystal structure of gp41. The synthesized ligands showed significant inhibitory activities against HIV gp41 6-helix bundle formation, HIV-1 mediated cell-cel
