1208004-07-2Relevant academic research and scientific papers
Carbonic Anhydrases inhibitory effects of new benzenesulfonamides synthesized by using superacid chemistry
Liu, Fei,Martin-Mingot, Agnès,Lecornué,Jouannetaud, Marie-Paule,Maresca, Alfonso,Thibaudeau, Sebastien,Supuran, Claudiu T.
, p. 886 - 891 (2013/02/23)
A series of benzofused sultams and fluorinated benzenesulfonamides were synthesized in superacid HF/SbF5 from simple N-allylic derivatives. Almost all of these original compounds showed micromolar inhibitory activities against carbonic anhydrases I and II
Superelectrophilic activation in superacid HF/SbF5 and synthesis of benzofused sultams
Liu, Fei,Martin-Mingot, Agnes,Jouannetaud, Marie-Paule,Zunino, Fabien,Thibaudeau, Sebastien
supporting information; experimental part, p. 868 - 871 (2010/04/27)
(Figure Presented) The synthesis of benzofused sultams and/or fluorlnated sulfonamides, starting from N-allyllc sulfonamides, was performed In superacid HF/ SbF5, through superelectrophilic activation. A dramatic effect of superacid composition on the selectivity of the reaction was shown and applied to the synthesis of cyclic 4-aminobenzenesulfonamides.
