120802-92-8Relevant academic research and scientific papers
Facile Synthesis of Natural Alkoxynaphthalene Analogues from Plant Alkoxybenzenes
Tsyganov, Dmitry V.,Krayushkin, Mikhail M.,Konyushkin, Leonid D.,Strelenko, Yuri A.,Semenova, Marina N.,Semenov, Victor V.
, p. 923 - 928 (2016/05/24)
Analogues of the bioactive natural alkoxynaphthalene pycnanthulignene D were synthesized by an efficient method. The starting plant allylalkoxybenzenes (1) are easily available from the plant essential oils of sassafras, dill, and parsley. The target 1-arylalkoxynaphthalenes (5) exhibited antiproliferative activity in a phenotypic sea urchin embryo assay.
Synthesis of podophyllotoxin and its derivatives via nicl2/nabh4 reduction of isoxazoline ring
Babu, Meduri Suresh,Rai, Kuria Madhavu Lokanatha
, p. 9555 - 9557 (2014/01/06)
A novel synthesis of podophyllotoxin was carried out in four steps. The key step was reduction of isoxazoline ring followed by diazotization and the resultant alkene was treated with Mn(OAc)3/CH3COOK to form podophyllotoxin.
A New Method for the Generation of Nitrile Oxides and Its Application to the Synthesis of 2-Isoxazolines
Hassner, Alfred,Rai, K. M. Lokanatha
, p. 57 - 59 (2007/10/02)
Reaction of aldoximes with chloramine-T leads to formation of nitrile oxides which can react in situ intra- or intermolecularly with olefinic compounds to produce isoxazolines in good yield.
