120802-98-4Relevant academic research and scientific papers
Sugar-based ethenyl ethers: Stereoselective dipolar cycloadditions of nitrile oxides
Desroses, Matthieu,Chery, Florence,Tatibouet, Arnaud,De Lucchi, Ottorino,Rollin, Patrick
, p. 2535 - 2539 (2002)
Selected sugar-based ethenyl ethers have been employed in 1,3-dipolar cycloaddition with nitrile oxides. In the D-fructo series, high diastereoselectivity was observed as compared with the 3-epimeric D-psico series.
Synthesis and pharmacological evaluation of 1,3,4-oxadiazole bearing bis(heterocycle) derivatives as anti-inflammatory and analgesic agents
Jayashankar,Lokanath Rai,Baskaran,Sathish
experimental part, p. 3898 - 3902 (2009/12/09)
A series of novel ether-linked bis(heterocycle)s have been synthesized via [3 + 2]-cycloaddition reaction of nitrile oxide with allyl alcohol followed by intramolecular 1,3-diploar cycloaddition reaction of nitrile imine with carbonyl group. All the newly
A novel synthesis of isoxazoles via 1,3-dipolar cycloaddition of nitrile oxides to acetyl acetone
Umesha,Kumar, K. Ajay,Rai, K. M. Lokanatha
, p. 1841 - 1846 (2007/10/03)
Nitrile oxides (2) isolated from the oxidative dehydrogenation of aldoximes (1) by chloramines-T react with acetyl acetone (3) to afford 4-acetyl-3-aryl-5-methyl isoxazoles (5) in good yield. All new compounds were characterized by IR, 1H NMR,
Intermodular 1,3-dipolar cycloaddition of nitrite oxides with vinyl acetate and acrylonitrile
Lokanatha Rai,Hassner, Alfred
, p. 242 - 245 (2007/10/03)
Reaction of several nitrile oxides 2, isolated from the oxidative dehydrogenation of aldoximes by chloramine-T, with vinyl acetate and acrylonitrile proceeds in better yield than if the nitrile oxides are generated in situ. Solvent effects are also consid
Intermolecular 1,3-dipolar cycloadditions of preformed nitrile oxides with phenyl vinyl sulphone
Rai, K.M. Lokanatha,Hassner
, p. 467 - 472 (2007/10/03)
Dipolar cycloadditions of nitrile oxides 2, isolated from the oxidative dehydrogenation of aldoximes by chloramine-T, with vinyl sulphone 3 are discussed.
A New Method for the Generation of Nitrile Oxides and Its Application to the Synthesis of 2-Isoxazolines
Hassner, Alfred,Rai, K. M. Lokanatha
, p. 57 - 59 (2007/10/02)
Reaction of aldoximes with chloramine-T leads to formation of nitrile oxides which can react in situ intra- or intermolecularly with olefinic compounds to produce isoxazolines in good yield.
