1208065-59-1

Basic information

• Product Name: C₁₇H₁₃NO₃S
• CAS NO: 1208065-59-1
• Molecular Weight: 311.361
• Mol File: 1208065-59-1.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: C₁₇H₁₃NO₃S(CAS DataBase Reference)
• NIST Chemistry Reference: C₁₇H₁₃NO₃S(1208065-59-1)
• EPA Substance Registry System: C₁₇H₁₃NO₃S(1208065-59-1)

Safety Data

• Hazardous Substances Data: 1208065-59-1(Hazardous Substances Data)

Upstream product

• 1082068-51-6 3-(4-thiomethoxyphenyl)-4-phenyl-1H-pyrrole-2,5.dione 

Relevant articles and documents

Synthesis and PGE2 production inhibition of 1H-furan-2,5-dione and 1H-pyrrole-2,5-dione derivatives

3,4-Diphenyl-substituted 1H-furan-2,5-dione and 1H-pyrrole-2,5-dione derivatives were synthesized and evaluated for the inhibitory activities on LPS-induced PGE2 production in RAW 264.7 macrophage cells. Both 1H-furan-2,5-dione and 1H-pyrrole-2,5-dione rings as main scaffolds were easily obtained using one of three synthetic methods. Among the compounds investigated, 1H-3-(4-sulfamoylphenyl)-4-phenyl-pyrrole-2,5-dione (6l) showed a strong inhibitory activity (IC50 = 0.61 μM) of PGE2 production.