1208099-40-4Relevant articles and documents
Facile synthesis of aminoalkyl naphthols and single crystal X-ray, computational studies on 1-[morpholino(thiophen-2-yl)methyl]naphthalen-2-ol
Harichandran, G.,Muthu, S.,Surya, C. P.
, (2021)
An efficient, eco-friendly protocol is developed for the synthesis of 1- (α-aminoalkyl)-2-naphthol derivatives via one-pot three-component reaction of 2-naphthol, aromatic aldehydes and piperidine or morpholine in the presence of Amberlite IRA-400 Cl resi
Revisiting the Betti Synthesis: Using a Cheap, Readily Available, Recyclable Clay Catalyst under Solventless Conditions
Bosica, Giovanna,Abdilla, Roderick,Demanuele, Kaylie
, p. 6127 - 6133 (2018)
One-pot multicomponent reactions have gained significant importance in recent years because they are usually more selective, simple, efficient, atom-economic and green than their multistep counterparts. The Betti synthesis involves the combination of aldehydes, amines and 2-naphthol to form compounds which can serve as catalysts or as biologically active compounds. In this study, Montmorillonite K30 was used as a heterogeneous catalyst for the Betti reaction at 60 °C in relatively short reaction times. Positively, it is cheap, readily and commercially available and requires no preparation, it can be used in neat conditions whilst minimizing excess reagent amounts. Most importantly, it is fully recoverable and can be recycled up to 5 times. In reactions involving secondary aliphatic amines, very good to excellent results were obtained whilst primary ones including benzylamine gave appreciable yields. In addition, the heteroaromatic aldehyde 4-pyridinecarboxaldehyde and the polyaromatic aldehyde 1-naphthaldehyde also gave encouraging results.
Gold nanoparticles deposited on MnO2 nanorods modified graphene oxide composite: A potential ternary nanocatalyst for efficient synthesis of betti bases and bisamides
Nayak, Pratap S.,Barik, Bapun,Achary, L. Satish K.,Kumar, Aniket,Dash, Priyabrat
, (2019/06/06)
The decoration of novel nanostructures such as nano particle and nanorod on the surface of graphene oxide (GO) generate potential heterogeneous nanocatalyst. Highlighting this, in the present work, we have designed a ternary GO-MnO2-Au nanocomposite by decorating MnO2nanorods on the surface of graphene oxide via hydrothermal method, followed by deposition of Au nanoparticles on GO-MnO2 surface. The prepared nanocomposite was thoroughly characterised by different instrumental techniques such as X-Ray diffraction (XRD),Fourier transform infrared spectroscopy (FTIR),Raman spectroscopy, Field emission scanning electron microscopy (FESEM), Transmission electron microscopy (TEM), High resolution Transmission electron microscopy (HRTEM), X-Ray photo electron spectroscopy (XPS), N2 adsorption desorption Brunauer–Emmett–Teller (BET) isotherm and Inductively coupled plasma - optical emission spectrometry (ICP-OES). FESEM and TEM images demonstrated that the MnO2 forms rod like structure having diameter of 60–100 nm and are uniformly distributed over the GO surface. HRTEM image clearly signifies gold (Au) nanoparticles having diameter of 7 ± 1.9 nm homogeneously distributed throughout the GO-MnO2 surface. Elementary state of Au and tetravalent nature of Mn as well as reduction of functional group after the decoration was confirmed from XPS studies. The catalyst GO-MnO2-Au was found to be the superior catalyst for synthesis of biologically active molecules such as Betti bases and Bisamides. The high catalytic activity of the materials can be attributed to the small and homogeneous distribution of gold nanoparticles, high redox potential of rod shaped MnO2 and the synergistic effect between GO, MnO2 and Au. All the reaction conditions were optimised by varying catalyst dosage, effect of solvent and temperature. The GO-MnO2-Au was easily recycled with minimal leaching and the product yield was found to be 85–90% after 4th cycle demonstrating the stability and durability of our nanocomposite.
A competent pot and atom-efficient synthesis of Betti bases over nanocrystalline MgO involving a modified Mannich type reaction
Karmakar, Bikash,Banerji, Julie
experimental part, p. 4957 - 4960 (2011/10/08)
A simple, efficient, and eco-friendly method for the synthesis of 1-(α-aminoalkyl) naphthols, the Betti bases, has been carried out over a basic nanocrystalline MgO catalyst in aqueous condition. The method has been applied for the synthesis of a range of compounds with variable functionalities in excellent yield and selectivity.
