1208128-24-8

Basic information

• Product Name: C₂₄H₂₁N₅O₄
• CAS NO: 1208128-24-8
• Molecular Weight: 443.462
• Mol File: 1208128-24-8.mol

Chemical Properties

• CAS DataBase Reference: C₂₄H₂₁N₅O₄(CAS DataBase Reference)
• NIST Chemistry Reference: C₂₄H₂₁N₅O₄(1208128-24-8)
• EPA Substance Registry System: C₂₄H₂₁N₅O₄(1208128-24-8)

Safety Data

• Hazardous Substances Data: 1208128-24-8(Hazardous Substances Data)

Upstream product

• 1208128-32-8 1-{5-[2-(benzyloxy)phenyl]-1,3,4-oxadiazol-2-yl}urea 
• 1208128-33-9 N-{5-[2-(benzyloxy)phenyl]-1,3,4-oxadiazol-2-yl}hydrazine carboxamide 
• 99-93-4 4-Hydroxyacetophenone 
• 55142-16-0 methyl 2-(benzyloxy)benzoate 
• 100-44-7 benzyl chloride 
• 81263-73-2 2-amino-5-(o-benzyloxyphenyl)-1,3,4-oxadiazole 
• 380335-36-4 2-benzyloxybenzoic acid hyrdrazide 
• 119-36-8 methyl salicylate 

Relevant articles and documents

A Novel Series of 2,5-Disubstituted 1,3,4-oxadiazoles: Synthesis and SAR Study for their Anticonvulsant Activity

In search for a better anticonvulsant drug and the importance of semicarbazones and 2,5-disubstituted 1,3,4-oxadiazoles as anticonvulsant pharmacophore, a series of novel substituted semicarbazones were designed, synthesized, and evaluated for their anticonvulsant activity. The chemical structures of the synthesized molecules were confirmed by elemental and spectral (IR, 1H NMR, 13C NMR and MS) analysis. The anticonvulsant activities of the compounds were investigated using maximal electroshock seizure and subcutaneous pentylenetetrazole (scPTZ) models. Efforts were also made to establish structure-activity relationships among synthesized compounds. The results of the present study validated that the pharmacophore model with four binding sites is essential for anticonvulsant activity.