120814-22-4Relevant academic research and scientific papers
A regioselectivity switch in Pd-catalyzed hydroallylation of alkynes
Ji, Ding-Wei,Hu, Yan-Cheng,Zheng, Hao,Zhao, Chao-Yang,Chen, Qing-An,Dong, Vy M.
, p. 6311 - 6315 (2019/07/04)
By exploiting the reactivity of a vinyl-Pd species, we control the regioselectivity in hydroallylation of alkynes under Pd-hydride catalysis. A monophosphine ligand and carboxylic acid combination promotes 1,5-dienes through a pathway involving isomerization of alkynes to allenes. In contrast, a bisphosphine ligand and copper cocatalyst favor 1,4-dienes via a mechanism that involves transmetalation. Our study highlights how to access different isomers by diverting a common organometallic intermediate.
Palladium-catalyzed tandem coupling reaction of alkyne, conjugated diene, and triethylborane
Takushima, Daiki,Fukushima, Masahiro,Satomura, Hideaki,Onodera, Gen,Kimura, Masanari
, p. 171 - 180 (2013/08/23)
Pd(0) catalyst promotes three-component coupling reactions of allylic alcohols and vinylcyclopropanes with terminal alkynes and triethylborane to provide (E)-1-substituted 2-ethyl-1,4-pentadienes and (E)-1-substituted 2-ethyl-1,4-heptadienes involving gem
OLIGOMETHYLENATION OF PHENYLALLENE WITH DIAZOMETHANE IN THE PRESENCE OF PALLADIUM DIACETATE
Lukin, K. A.,Zefirov, N. S.
, p. 82 - 86 (2007/10/02)
In the reaction of phenylallene with diazomethane in the presence of palladium(II) acetate oligomethylenation takes place in addition to cyclopropanation.It leads to the inclusion of three and four equivalences of methylene in the allene molecule.
