120821-68-3Relevant academic research and scientific papers
Synthesis of 2-Aryl-1,2,4-triazolopyrimidines
Prasad, V.S.R.,Reddy, K.Kondal
, p. 2617 - 2622 (2007/10/02)
N-2-Pyrimidylarylamidines (2) obtained by the reaction of 2-aminopyrimidines (1) with aryl cyanides in the presence of anhydrous aluminium chloride have been converted into 2-aryl-1,2,4-triazolopyrimidines (4) by oxidative cyclisation in the presence of lead tetraacetate.
Synthesis of 2-Aryltriazolopyrimidines
Kamala, K.,Rao, P. Jayaprasad,Reddy, K. Kondal
, p. 3791 - 3793 (2007/10/02)
2-Aroylamino)pyrimidines (4) have been converted into 1-(2-pyrimidyl)-5-aryl-1H-tetrazoles (6) by treatment with PCl5 followed by azidolysis in aqueous acetone solution.Pyrolysis of 6 in decalin gave 2-aryltriazolopyrimidines (8).A reasonable pathway for the formation of 8 from 6 is suggested.Structures of all the compounds have been established by elemental analysis and spectral data.
