1208334-60-4Relevant academic research and scientific papers
Polyethylene glycol (PEG-400) as an efficient and recyclable reaction medium for one-pot synthesis of substituted pyrroles under catalyst-free conditions
Kumar, Tulam Vijaya,Rao, Ch. Rama Koteswara,Mukkanti,Mainkar, Prathama S.
, p. 1457 - 1461 (2015)
Polyethylene glycol (PEG-400) was found to be an effective and nontoxic reaction medium for the one-pot synthesis of substituted pyrroles under catalyst-free conditions in excellent yields. Environmental acceptability, low cost, high yields and recyclabil
β-Cyclodextrin as a recyclable catalyst: Aqueous phase one-pot four-component synthesis of polyfunctionalized pyrroles
Konkala, Karnakar,Chowrasia, Rakhi,Manjari, Padma S.,Domingues, Nelson L. C.,Katla, Ramesh
, p. 43339 - 43344 (2016/05/24)
An elegant, mild and straightforward methodology was explored for the first time towards the synthesis of polyfunctionalized pyrroles using β-cyclodextrin as a reusable supramolecular catalyst in aqueous medium. The present method provides various diversely substituted pyrroles from the commercially available synthons in good to excellent yields. The advantages of this novel protocol are use of environmentally benign reaction medium and recyclability of β-cyclodextrin over the existing methods.
Three-component direct synthesis of substituted pyrroles from easily accessible chemical moieties using hypervalent iodine reagent
Jadhav, Nikhil C.,Jagadhane, Prashant B.,Patile, Hemlata V.,Telvekar, Vikas N.
, p. 3019 - 3021 (2013/06/27)
A novel and simple three-component system has been developed to synthesize substituted pyrroles from corresponding amines and nitrostyrenes using (diacetoxyiodo)benzene at reflux temperature in ethanol. The good to excellent yields were obtained with different types of functional groups.
Iron(III)-catalyzed four-component coupling reaction of 1,3-dicarbonyl compounds, amines, aldehydes, and nitroalkanes: A simple and direct synthesis of functionalized pyrroles
Maiti, Sukhendu,Biswas, Srijit,Jana, Umasish
experimental part, p. 1674 - 1683 (2010/05/01)
Chemical Equation Represented A simple, convenient, and multicomponent coupling strategy for the synthesis of highly functionalized pyrroles catalyzed by iron(III) salts has been developed. This strategy demonstrated fourcomponent coupling reactions of 1,3-dicarbonyl compounds, amines, aromatic aldehydes, and nitroalkanes without an inert atmosphere. This methodology provides an alternative approach for easy access of highly substituted pyrroles in moderate to very good yields using four simple and readily available building blocks via one-pot tandem reaction. Notably, this method is very cheap, straightforward, and environmentally friendly compared to the existing methods.
