1208347-73-2Relevant academic research and scientific papers
Rapid two-step synthesis of drug-like polycyclic substances by sequential multi-catalysis cascade reactions
Ramachary, Dhevalapally B.,Mondal, Rumpa,Venkaiah, Chintalapudi
, p. 321 - 325 (2010)
An efficient amino acid-/self-/base-/ruthenium-/thermal-catalyzed two-step process for the synthesis of functionalized drug-like carbocycles was achieved through combinations of cascade TCRA/C-allylation/enyne-RCM/Diels-Alder reactions as key steps starting from simple acyclic substrates. In this communication, we report the two-step synthesis of drug-like carbocycles through a combination of organocatalysis with ruthenium-catalysis.
