1208353-99-4

Basic information

• Product Name: (3S,14R)-ochratoxin A
• CAS NO: 1208353-99-4
• Molecular Weight: 403.819
• Mol File: 1208353-99-4.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: (3S,14R)-ochratoxin A(CAS DataBase Reference)
• NIST Chemistry Reference: (3S,14R)-ochratoxin A(1208353-99-4)
• EPA Substance Registry System: (3S,14R)-ochratoxin A(1208353-99-4)

Safety Data

• Hazardous Substances Data: 1208353-99-4(Hazardous Substances Data)

Relevant articles and documents

Total synthesis and cytotoxicity evaluation of all ochratoxin A stereoisomers

The mycotoxin ochratoxin A is a potent inhibitor of the protein biosynthesis and known to be cytotoxic in nanomolar concentrations. In order to investigate the relationship between stereochemistry and cytotoxicity of this compound, all four ochratoxin A stereoisomers have been synthesized. Using the liver cell line Hep G2, the compounds were tested for cytotoxic and apoptotic potential. It could be shown, that the l-configuration of the phenylalanine moiety of the molecule is mostly responsible for the high cytotoxicity of ochratoxin A while the stereocenter at the dihydroisocoumarine structure is of less importance.