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1208361-39-0

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1208361-39-0 Usage

General Description

Methyl 4-bromo-1-aminopyrrole-2-carboxylate hydrochloride is a chemical compound that belongs to the class of pyrrole derivatives. It is a synthetic intermediate used in the pharmaceutical industry for the production of various drugs and active pharmaceutical ingredients. The hydrochloride salt form of this compound makes it more water-soluble and easier to handle in laboratory settings. It is commonly used as a building block for the synthesis of organic molecules, including potential drug candidates. The compound is characterized by the presence of a bromine atom and an amino group on the pyrrole ring, which gives it unique reactivity and versatility in organic synthesis.

Check Digit Verification of cas no

The CAS Registry Mumber 1208361-39-0 includes 10 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 7 digits, 1,2,0,8,3,6 and 1 respectively; the second part has 2 digits, 3 and 9 respectively.
Calculate Digit Verification of CAS Registry Number 1208361-39:
(9*1)+(8*2)+(7*0)+(6*8)+(5*3)+(4*6)+(3*1)+(2*3)+(1*9)=130
130 % 10 = 0
So 1208361-39-0 is a valid CAS Registry Number.

1208361-39-0SDS

SAFETY DATA SHEETS

According to Globally Harmonized System of Classification and Labelling of Chemicals (GHS) - Sixth revised edition

Version: 1.0

Creation Date: Aug 19, 2017

Revision Date: Aug 19, 2017

1.Identification

1.1 GHS Product identifier

Product name methyl 1-amino-4-bromopyrrole-2-carboxylate

1.2 Other means of identification

Product number -
Other names Methyl 1-amino-4-bromo-1H-pyrrole-2-carboxylate

1.3 Recommended use of the chemical and restrictions on use

Identified uses For industry use only.
Uses advised against no data available

1.4 Supplier's details

1.5 Emergency phone number

Emergency phone number -
Service hours Monday to Friday, 9am-5pm (Standard time zone: UTC/GMT +8 hours).

More Details:1208361-39-0 SDS

1208361-39-0Relevant articles and documents

ERK1/2 protein kinase inhibitor and application thereof

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Paragraph 0127-0129, (2021/03/31)

The present invention provides a compound represented by formula (I), or isomers and pharmaceutically acceptable salts thereof, and uses of the compound, isomer and pharmaceutically acceptable salts in preparation of ERK1/2 mediated disease drugs.

6-bromo-3H-pyrrolo(2,1-f)(1,2,4)triazine-4-ketone preparation method

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, (2019/02/06)

The invention belongs to the technical field of medicine and specifically relates to a 6-bromo-3H-pyrrolo(2,1-f)(1,2,4)triazine-4-ketone preparation method. The method comprises the following steps: reacting 2,5-dimethoxy tetrahydrofuran with tert-butylcarbazate to obtain compound IV; then reacting with trichloro-acetic chloride to obtain compound V; bromizing to obtain compound Vi; performing esterification reaction to obtain compound VII; finally, cyclizing to obtain 6-bromo-3H-pyrrolo(2,1-f)(1,2,4)triazine-4-ketone. Compared with the prior art, the preparation method disclosed by the invention greatly improves the yield and the purity of 6-bromo-3H-pyrrolo(2,1-f)(1,2,4)triazine-4-ketone, reduces production cost and has good application value.

TGF BETA RECEPTOR ANTAGONISTS

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Page/Page column 151; 152, (2017/03/08)

The invention relates generally to compounds that modulate the activity of TGFβR-1 and TGFβ R-2, pharmaceutical compositions containing said compounds and methods of treating proliferative disorders and disorders of dysregulated apoptosis, such as cancer, utilizing the compounds of the invention.

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