1208387-35-2Relevant academic research and scientific papers
Concise route to the key intermediate for divergent synthesis of C7-substituted fluoroquinolone derivatives
Zhang, Xin,Mu, Feng,Robinson, Bobby,Wang, Pengfei
supporting information; experimental part, p. 600 - 601 (2010/04/05)
A concise route to ethyl 7-bromo-1-cyclopropyl-6,8-difluoro-4-quinolone-3-carboxylate has been developed. This compound is a key intermediate for divergent synthesis of various C7-substituted fluoroquinolones, a group of potent topoisomerase II inhibitors
