120848-81-9Relevant academic research and scientific papers
Metal-free, aerobic dioxygenation of alkenes using simple hydroxamic acid derivatives
Giglio, Benjamin C.,Schmidt, Valerie A.,Alexanian, Erik J.
, p. 13320 - 13322 (2011/10/10)
The dioxygenation of alkenes using molecular oxygen and a simple hydroxamic acid derivative has been achieved. The reaction system consists of readily prepared methyl N-hydroxy-N-phenylcarbamate and molecular oxygen with a radical initiator, offering an alternative to common dioxygenation processes catalyzed by precious transition metals. This transformation capitalizes on the unique reactivity profile of hydroxamic acid derivatives in radical-mediated alkene addition processes.
