1208500-39-3

Basic information

• Product Name: 1,4-bis(2-(methylthio)phenyl)buta-1,3-diyne
• Synonyms: 1,4-bis(2-(methylthio)phenyl)buta-1,3-diyne
• CAS NO: 1208500-39-3
• Molecular Weight: 294.441
• Mol File: 1208500-39-3.mol
• Article Data: 3

Chemical Properties

• CAS DataBase Reference: 1,4-bis(2-(methylthio)phenyl)buta-1,3-diyne(CAS DataBase Reference)
• NIST Chemistry Reference: 1,4-bis(2-(methylthio)phenyl)buta-1,3-diyne(1208500-39-3)
• EPA Substance Registry System: 1,4-bis(2-(methylthio)phenyl)buta-1,3-diyne(1208500-39-3)

Safety Data

• Hazardous Substances Data: 1208500-39-3(Hazardous Substances Data)

Upstream product

• 415680-02-3 trimethyl{[2-(methylsulfanyl)phenyl]ethynyl}silane 
• 78331-59-6 Diethyl α-allyl-α-bromomalonate 
• 78905-08-5 <(o-methylthio)phenyl>acetylene 
• 1208500-32-6 1-(2-iodoethynyl)-2-methoxybenzene 

Downstream Products

• 241-13-4 Bis(benzo<4,5>thieno)<3,2-b:2',3'-d>thiophen 

Relevant articles and documents

Linear and Angular Heteroacenes from Double-Electrophilic Cyclization (DEC) and DEC-Reductive Elimination of Diynes

Linear and angular heteroacenes are prepared from terminal alkynes bearing tethered nucleophiles in two steps. Linear heteroacenes are formed from the homocoupling of these alkynes followed by reaction with a double electrophile (ECl2) to induce a tricyclization reaction cascade involving double-electrophilic cyclization (DEC). Related angular heteroacenes are formed from the prior substitution of the chloro groups in ECl2 with the same terminal alkyne followed by reaction with AuCl3 to produce a DEC-reductive-elimination (DECRE) reaction.

Iodine/Palladium approaches to the synthesis of polyheterocyclic compounds

Chemical Equation Represented A simple, straightforward strategy for the synthesis of polyheterocyclic compounds (PHCs) is reported, which involves iterative cycles of palladium-catalyzed Sonogashira coupling, followed by iodocyclization using I2 or ICI. A variety of heterocyclic units, including benzofurans, benzothiophenes, indoles, and isocoumarins, can be efficiently incorporated under mild reaction conditions. In addition, variations of this strategy afford a variety of linked and fused PHCs.