120871-54-7Relevant academic research and scientific papers
CYCLISATION DE N-TOSYL OXIRANES-PROPYLAMINES: SYNTHESE D'HETEROCYCLES AZOTES.
Nuhrich, A.,Moulines, J.
, p. 3075 - 3088 (2007/10/02)
The cyclisation of N-tosyl-oxiranepropylamines is accomplished in aqueous basic medium and in anhydrous acid medium as well.In most cases, this reaction occurs by a regiospecific 5-exo-tet. ring closure and affords N-tosyl-2-pyrrolidinemethanols in high y
SYNTHESIS OF MONOCYCLIC ANALOGUES OF A POTENT THROMBOXANE RECEPTOR ANTAGONIST, (+/-)-(5Z)-7-BICYCLOHEPT-2-EXO-YL>HEPTENOIC ACID (S-145)
Kawada, Kenji,Tsushima, Tadahiko
, p. 573 - 578 (2007/10/02)
Several monocyclic analogues of the potent thromboxane-A2 receptor antagonist S-145, i.e. cyclohexane, cyclopentane, tetrahydrofuran, and pyrrolidine, as well as the biclooctane one were synthesized using allylation via oxime dianion and the Barton's method for oxime reduction in the key steps.
