1209000-34-9Relevant academic research and scientific papers
Synthesis of flavonoid 7-O-β-D-glycosides by phase transfer catalysis
Wu, Zheng,Jiang, Ling,Chen, He,Wang, Qiu-An
experimental part, p. 195 - 197 (2009/11/30)
Six flavonoid 7-O-β-D-glycosides 1a-3a and 1b-3b were synthesised from the flavones 7a and 7b by glycosidation and deacetylation with the corresponding a-acetylglycosyl bromides. 7a and 7b were prepared in high yield by an improved Baker-Venkataraman rearrangement using 2, 4- dihydro×yacetophenone as starting material and tetrabutylammonium bromide (TBAB) as a phase transfer catalyst. The glycosidation procedure was modified by using anhydrous K2CO3 in a solvent mixture of DMF/acetone (3:2v/v) and TBAB as a phase transfer catalyst.
