1209008-53-6Relevant academic research and scientific papers
A novel bridged nucleoside bearing a conformationally switchable sugar moiety in response to redox changes
Baba, Takeshi,Kodama, Tetsuya,Mori, Kazuto,Imanishi, Takeshi,Obika, Satoshi
supporting information; experimental part, p. 8058 - 8060 (2011/01/03)
A novel nucleoside analog with a disulfide bridge structure at the sugar moiety, which shows redox-responsive reversibility of the sugar conformation due to formation and scission of the disulfide bond, was designed and synthesized.
Synthesis, RNA selective hybridization and high nuclease resistance of an oligonucleotide containing novel bridged nucleic acid with cyclic urea structure
Nishida, Masaru,Baba, Takeshi,Kodama, Tetsuya,Yahara, Aiko,Imanishi, Takeshi,Obika, Satoshi
supporting information; experimental part, p. 5283 - 5285 (2010/09/11)
A novel bridged nucleic acid bearing cyclic urea structure was successfully synthesized and introduced into oligonucleotide, displaying attractive characteristics of highly RNA selective hybridization ability and excellent resistance towards nuclease degradation.
