120917-32-0Relevant academic research and scientific papers
Photochemical Rearrangement of Chiral Oxaziridines in Continuous Flow: Application Toward the Scale-Up of a Chiral Bicyclic Lactam
Cochran, John E.,Waal, Nathan
, p. 1533 - 1539 (2016)
A method for synthesizing chiral lactams from chiral oxaziridines in continuous flow is described. The oxaziridines are readily available from cyclic ketones. Photolysis of the oxaziridines using the Booker-Milburn flow system provides conversion to the chiral lactams in good yield and short residence times. Application of this chemistry toward the synthesis of a chiral bicyclic lactam is described.
NOVEL, ENANTIOSELECTIVE SYNTHESIS OF VICINAL CYCLOHEXANE-DIAMINES AS KEY-INTERMEDIATES FOR HIGHLY SELECTIVE OPIOID KAPPA AND SIGMA AGONISTS.
Schlichter, Wolfgang H.,Frahm, August W.
, p. 329 - 332 (2007/10/02)
Enantiomers of Cyclohexane-1,2-diamines have been synthesized via two different synthetic approaches by asymmetric catalytic hydrogenation.
ENANTIOSELECTIVE SYNTHESIS OF OXA-SPIRO COMPOUNDS
Desmaele, Didier,d'Angelo, Jean
, p. 345 - 348 (2007/10/02)
Optically active compound 10b, efficiently prepared from imine 8b, was transformed into oxa-spiro derivatives 15 and 16.
