120929-95-5

Upstream product

• 88722-50-3 5-amino-1-(2-amino-4-trifluoromethylphenyl)-3-methylthio-1H-1,2,4-triazole 
• 1655-07-8 ethyl 2-oxocyclohexane carboxylate 

Relevant academic research and scientific papers

On Triazoles XVI . The Reaction of 5-Amino-1,2,4-triazoles with β- and γ-Oxo Esters. A Novel N-Carbonylation Reaction

5-Amino-1,2,4-triazoles reacted with alifatic β-oxo-esters to yield besides the unexpected 1,2,4-triazolo-1,3,5-benzotriazepin-5-one derivative 7 either the corresponding esters 5 and 6 or a 1:2 condensation product 8.To the contrary alicyclic and heterocyclic β-oxo-esters formed in the above reaction only derivatives 7.The proposed mechanism of the formation of 7 involving a novel N-carbonylation reaction was proved by the isolation of the by-products and the intermediate of the reaction.Repeating the above reaction with γ-oxo-esters, namely the ethyl levulinate, derivatives 17 and 18, respectively, representing two new ring systems were obtained.