1209413-32-0Relevant academic research and scientific papers
Tuneable access to indole, indolone, and cinnoline derivatives from a common 1,4-diketone Michael acceptor
Abdelli, Abderrahmen,Efrit, Mohamed Lotfi,El-Marrouki, Dalel,Gros, Philippe C.,M’Rabet, Hédi,Touchet, Sabrina
, p. 1722 - 1731 (2020)
A convergent strategy is reported for the construction of nitrogen-containing heterocycles from common substrates: 1,4-diketones and primary amines. Indeed, by just varying the substrates, the substituents, or the heating mode, it is possible to selectively synthesize indole, indolone (1,5,6,7-tetrahydroindol-4-one), or cinnoline (5,6,7,8-tetrahydrocinnoline) derivatives in moderate to excellent yields.
The first DMAP-mediated palladium-free Tsuji-Trost-type reaction of cyclic and acyclic Baylis-Hillman alcohols with active methylene compounds
Mhasni, Olfa,Rezgui, Farhat
experimental part, p. 586 - 587 (2010/04/02)
Direct allylic substitution of cyclic Baylis-Hillman alcohols with active methylene compounds under modified Taber's conditions (DMAP, toluene, reflux, 4 ? molecular sieves), with no Pd catalysts/activating agents, as is usually required for the process, affords the C-allylation products in moderate to good yields.
