1209459-16-4

Usage

Uses

Used in Pharmaceutical Industry:
2-Bromopyrimidine-4-carbonitrile is used as a building block for the synthesis of various biologically active compounds and pharmaceutical agents. Its unique structure allows for the development of a wide range of derivatives with diverse applications in medicine.
Used in Agrochemical Synthesis:
In the agrochemical industry, 2-Bromopyrimidine-4-carbonitrile is utilized as an intermediate in the synthesis of various agrochemicals, contributing to the development of effective products for agricultural applications.
Used in Organic Chemistry and Drug Discovery:
As an important reagent, 2-Bromopyrimidine-4-carbonitrile is employed in the preparation of a broad spectrum of derivatives, playing a crucial role in advancing the field of organic chemistry and facilitating drug discovery efforts.

Upstream product

• 1643-19-2 tetrabutylammomium bromide 
• 7460-56-2 2-hydroxy-pyrimidine-4-carbaldehyde oxime 

Downstream Products

• 1448347-91-8 (3S)-tert-butyl 3-((1-(2-chlorophenyl)-2-((3,3-difluorocyclobutyl)amino)-2-oxoethyl)(3,5-difluorophenyl)carbamoyl)-4-(4-cyanopyrimidin-2-yl)-5-oxopiperazine-1-carboxylate 
• 1448346-71-1 (S)-N-((S)-1-(2-chlorophenyl)-2-((3,3-difluorocyclobutyl)amino)-2-oxoethyl)-1-(4-cyanopyrimidin-2-yl)-N-(3,5-difluorophenyl)-6-oxopiperazine-2-carboxamide 

Relevant academic research and scientific papers

THERAPEUTICALLY ACTIVE COMPOUNDS AND THEIR METHODS OF USE

Provided are methods of treating a cancer characterized by the presence of a mutant allele of IDH1/2 comprising administering to a subject in need thereof a compound described here.

THERAPEUTICALLY ACTIVE COMPOUNDS AND USE THEREOF

Provided are therapeutically active compounds and the use in manufacture of medicaments for treating a cancer characterized by the presence of a mutant allele of IDH1.

THERAPEUTICALLY ACTIVE COMPOUNDS AND THEIR METHODS OF USE

Provided are methods of treating a cancer characterized by the presence of a mutant allele of IDH1/2 comprising administering to a subject in need thereof a compound described here.

THERAPEUTICALLY ACTIVE COMPOUNDS AND THEIR METHODS OF USE

Provided are methods of treating a cancer characterized by the presence of a mutant allele of IDH1/2 comprising administering to a subject in need thereof a compound described here.

THERAPEUTICALLY ACTIVE COMPOSITIONS AND THEIR METHODS OF USE

Provided are methods of treating a cancer characterized by the presence of a mutant allele of IDH1/2 comprising administering to a subject in need thereof a compound described here.