1209494-86-9Relevant academic research and scientific papers
Preparation of 2-sulfonyl-1,2,3-triazoles by base-promoted 1,2-rearrangement of a sulfonyl group
Yamauchi, Motoshi,Miura, Tomoya,Murakami, Masahiro
experimental part, p. 177 - 181 (2010/04/29)
1,2-Rearrangement of a sulfonyl group occurs on treatment of 1-sulfonyl-1,2,3-triazoles with a catalytic amount of 4-dimethylaminopyridine (DMAP) in acetonitrile to give an equilibrium mixture of 1-sulfonyl- and 2-sulfonyl derivatives, with considerable predominance of the latter. Subsequent acidic treatment of the mixture caused selective hydrolysis of the 1-sulfonyl derivative, which led to the isolation of the 2-sulfonyl-1,2,3-triazole in good total yield in a pure form.
