120950-99-4Relevant academic research and scientific papers
SYNTHESIS OF β-SILYL KETONES VIA REACTION OF TRIMETHYLSILYLLITHIUM WITH UNSATURATED HYDRAZONES. APPLICATION TO THE SYNTHESIS OF BREVICOMIN
Hudrlik, Paul F.,Hudrlik, Anne M.,Yimenu, Tilahun,Waugh, Morris A.,Nagendrappa, G.
, p. 3791 - 3804 (2007/10/02)
Trimethylsilyllithium undergoes conjugate addition to dimethylhydrazones of α,β-unsaturated ketones.The resulting metalloenamine intermediates can be alkylated, and the resulting hydrazone products cleaved to give α-substitued-β-silyl ketones.These reacti
