120962-75-6Relevant academic research and scientific papers
3-Oxa-15-cyclohexyl prostaglandin DP receptor agonists as topical antiglaucoma agents.
Hellberg, Mark R,Conrow, Raymond E,Sharif, Najam A,McLaughlin, Marsha A,Bishop, John E,Crider, Julie Y,Dean, W Dennis,DeWolf, Kevin A,Pierce, David R,Sallee, Verney L,Selliah, Robert D,Severns, Bryon S,Sproull, Steven J,Williams, Gary W,Zinke, Paul W,Klimko, Peter G
, p. 2031 - 2049 (2010/12/01)
A series of prostaglandin DP agonists containing a 3-oxa-15-cyclohexyl motif was synthesized and evaluated in several in vitro and in vivo biological assays. The reference compound ZK 118.182 (9beta-chloro-15-cyclohexyl-3-oxa-omega-pentanor PGF(2alpha)) i
Synthesis of novel prostaglandins containing a boronate in the α chain
Feng, Zixia,Hellberg, Mark
, p. 5813 - 5816 (2007/10/03)
A novel class of prostaglandins containing a boronate in the α chain have been synthesized. The key steps in the synthesis were the preparation of the ylide containing the boronate and the subsequent Wittig reaction using the ylide. (C) 2000 Elsevier Scie
