120982-52-7Relevant academic research and scientific papers
1H-pyrazole-1-alkanamides, antiarrhythmic compositions and use
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, (2008/06/13)
N-[(disubstituted amino)alkyl]-3,4 (or 4,5)-diaryl-1H-pyrazole-1-acetamides and pyrazole-1-propanamides, useful for treating cardiac arrhythmias in mammals, are prepared by reacting a lower-alkyl ester of pyrazole-1-acetic or propanoic acid with an appropriate diamine or by reacting a lower-alkyl ester of a pyrazole-1-acetic or propanoic acid with an ω-aminoalkanol, followed by activation of the alcohol and displacement by an appropriate amine.
