120985-24-2Relevant academic research and scientific papers
Formation of seven- and eight-membered rings by Mn(III)-based oxidative free-radical cyclization
Snider, Barry B.,Merritt, John E.
, p. 8663 - 8678 (2007/10/02)
Oxidative free-radical cyclizations of acetoacetates 1, 8, 17, and 20 with Mn(OAc)3·2H2 and Cu(OAc)2·H2O in acetic acid provide cycloheptenes and cyclooctenes in moderate to good yield. Tandem cyclizations of 28, 35 and 51 provide bicyclo[4.2.1]nonanes, bicyclo[5.2.1]decanes, bicyclo[5.3.0]decanes and bicyclo[6.3.0]undecanes.
FORMATION OF SEVEN- AND EIGHT-MEMBERED RINGS BY MANGANESE(III)-BASED OXIDATIVE FREE RADICAL CYCLIZATION.
Merritt, John E.,Sasson, Marvin,Kates, Steven A.,Snider, Barry B.
, p. 5209 - 5212 (2007/10/02)
Oxidative free radical cyclizations of β-ketoesters 1,5,11, and 14 with Mn(OAc)3*2H2O and Cu(OAc)2*H2O proceed in moderate yield to give seven- and eight-membered rings.The regiochemistry of the cyclization and oxidative termination are described.
