1210052-12-2

Upstream product

• 1210052-04-2 9-(2',3',5'-tri-O-tert-butyldimethylsilyl-β-D-ribofuranosyl)-2-benzylamino-purine 
• 1260177-41-0 (2R,3R,4R,5R)-2-(acetoxymethyl)-5-(2-chloro-9H-purin-9-yl)tetrahydrofuran-3,4-diyl diacetate 
• 100-46-9 benzylamine 
• 107037-21-8 2-amino-9-(2',3',5'-tri-O-acetyl-β-D-ribofuranosyl)purine 

Relevant academic research and scientific papers

Investigations into the origin of the molecular recognition of several adenosine deaminase inhibitors

Inhibitors of adenosine deaminase (ADA, EC 3.5.4.4) are potential therapeutic agents for the treatment of various health disorders. Several highly potent inhibitors were previously identified, yet they exhibit unacceptable toxicities. We performed a SAR s

N2-Modified 2-aminopurine ribonucleosides as minor-groove-modulating adenosine replacements in duplex RNA

"Chemical equation presented" Nucleoside analogs that project substituents Into the minor groove when incorporated into duplex RNA perturb the binding of proteins and can affect base pairing specificity. The synthesis of 2-amlnopurine ribonucleoside analo