121006-87-9

Upstream product

• 6341-92-0 6-chloroisatin 
• 4341-53-1 6-chloro-1H-indole-2,3-dione-3-thiosemicarbazone 
• 135-73-9 2-Bromo-4'-phenylacetophenone 

Downstream Products

• 121006-95-9 1-Biphenyl-4-yl-8-chloro-3-thia-4,5,10,10b-tetraaza-cyclopenta[a]fluorene 

Relevant academic research and scientific papers

Heterocyclic Systems Containing Bridgehead Nitrogen Atom: Synthesis of Thiazolotriazinoindoles and Isomeric Thiazolotriazinoindoles

8-Bromo- and 7-chloro-5H-2,3-dihydrotriazinoindole-3-thiones (II) on condensation with α-halogenoketones give 5H-3-aroylmethylthio-8-bromo- and 5H-3-aroylmethylthio-7-chlorotriazinoindole hydrohalides (III) which undergo PPA cyclization to furnish 3-aryl-7-bromo- and 3-aryl-8-chloro-thiazolotriazinoindoles (IV) and not the angular isomeric 1-aryl-7-bromo- and 1-aryl-8-chloro-thiazolotriazinoindoles (VI).The unequivocal synthesis of the latter (VI) has also been accomplished.