121029-76-3Relevant academic research and scientific papers
Enantioselective Access to 2,7-Cis-Disubstituted Oxepanes: Formal Synthesis of (+)-Isolaurepan
Carreno, M. Carmen,Des Mazery, Renaud,Urbano, Antonio,Colobert, Francoise,Solladie, Guy
, p. 297 - 299 (2007/10/03)
(Matrix presented) The asymmetric synthesis of 2,7-cis-disubstituted oxepanes bearing a sulfoxide is achieved from commercially available precursors in only five steps. The key step is the highly diastereoselective Et 3SiH/TMSOTf-promoted reduc
Total synthesis of brevetoxin B. 1. First generation strategies and new approaches to oxepane systems
Nicolaou,Hwang,Duggan,Nugiel,Abe,Bal Reddy,DeFrees,Reddy,Awartani,Conley,Rutjes,Theodorakis
, p. 10227 - 10238 (2007/10/03)
The first generation strategies toward the total synthesis of brevetoxin B (1) are presented and the syntheses of the key intermediates 3, 4, 5, 67, 83, and 94-98 required for the projected construction are described. The earliest and most convergent stra
