121030-33-9Relevant articles and documents
Chemokine receptor binding heterocyclic compounds with enhanced efficacy
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, (2008/06/13)
The invention relates to heterocyclic compounds consisting of a core nitrogen atom surrounded by three pendant groups, wherein two of the three pendant groups are preferably benzimidazolyl methyl and tetrahydroquinolyl, and the third pendant group contains N and optionally contains additional rings. The compounds bind to chemokine receptors, including CXCR4 and CCR5, and demonstrate protective effects against infection of target cells by a human immunodeficiency virus (HIV).
5'-{[(Z)-4-amino-2-butenyl]methylamino}-5'-deoxy-adenosine: A potent enzyme-activated irreversible inhibitor of S-adenosyl-L-methionine decarboxylase from Escherichia coli
Casara,Marchal,Wagner,Danzin
, p. 9111 - 9113 (2007/10/02)
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