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1210344-25-4

((3S,4S,5R)-6-allyloxy-3,4,5-tris-benzyloxy-2-hydroxymethyl-tetrahydro-pyran-2-yl)-methanol is a chemical with a specific purpose. Lookchem provides you with multiple data and supplier information of this chemical.

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  • 1210344-25-4 Structure

  • Basic information

    1. Product Name: ((3S,4S,5R)-6-allyloxy-3,4,5-tris-benzyloxy-2-hydroxymethyl-tetrahydro-pyran-2-yl)-methanol
    2. Synonyms: ((3S,4S,5R)-6-allyloxy-3,4,5-tris-benzyloxy-2-hydroxymethyl-tetrahydro-pyran-2-yl)-methanol
    3. CAS NO:1210344-25-4
    4. Molecular Formula:
    5. Molecular Weight: 520.623
    6. EINECS: N/A
    7. Product Categories: N/A
    8. Mol File: 1210344-25-4.mol

  • Chemical Properties

    1. Melting Point: N/A
    2. Boiling Point: N/A
    3. Flash Point: N/A
    4. Appearance: N/A
    5. Density: N/A
    6. Refractive Index: N/A
    7. Storage Temp.: N/A
    8. Solubility: N/A
    9. CAS DataBase Reference: ((3S,4S,5R)-6-allyloxy-3,4,5-tris-benzyloxy-2-hydroxymethyl-tetrahydro-pyran-2-yl)-methanol(CAS DataBase Reference)
    10. NIST Chemistry Reference: ((3S,4S,5R)-6-allyloxy-3,4,5-tris-benzyloxy-2-hydroxymethyl-tetrahydro-pyran-2-yl)-methanol(1210344-25-4)
    11. EPA Substance Registry System: ((3S,4S,5R)-6-allyloxy-3,4,5-tris-benzyloxy-2-hydroxymethyl-tetrahydro-pyran-2-yl)-methanol(1210344-25-4)

  • Safety Data

    1. Hazard Codes: N/A
    2. Statements: N/A
    3. Safety Statements: N/A
    4. WGK Germany:
    5. RTECS:
    6. HazardClass: N/A
    7. PackingGroup: N/A
    8. Hazardous Substances Data: 1210344-25-4(Hazardous Substances Data)

1210344-25-4 Usage

Check Digit Verification of cas no

The CAS Registry Mumber 1210344-25-4 includes 10 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 7 digits, 1,2,1,0,3,4 and 4 respectively; the second part has 2 digits, 2 and 5 respectively.
Calculate Digit Verification of CAS Registry Number 1210344-25:
(9*1)+(8*2)+(7*1)+(6*0)+(5*3)+(4*4)+(3*4)+(2*2)+(1*5)=84
84 % 10 = 4
So 1210344-25-4 is a valid CAS Registry Number.

1210344-25-4Relevant articles and documents

Discovery of a clinical candidate from the structurally unique dioxa-bicyclo[3.2.1]octane Class of sodium-dependent glucose cotransporter 2 inhibitors

Mascitti, Vincent,Maurer, Tristan S.,Robinson, Ralph P.,Bian, Jianwei,Boustany-Kari, Carine M.,Brandt, Thomas,Collman, Benjamin M.,Kalgutkar, Amit S.,Klenotic, Michelle K.,Leininger, Michael T.,Lowe, André,Maguire, Robert J.,Masterson, Victoria M.,Miao, Zhuang,Mukaiyama, Emi,Patel, Jigna D.,Pettersen, John C.,Préville, Cathy,Samas, Brian,She, Li,Sobol, Zhanna,Steppan, Claire M.,Stevens, Benjamin D.,Thuma, Benjamin A.,Tugnait, Meera,Zeng, Dongxiang,Zhu, Tong

, p. 2952 - 2960 (2011)

Compound 4 (PF-04971729) belongs to a new class of potent and selective sodium-dependent glucose cotransporter 2 inhibitors incorporating a unique dioxa-bicyclo[3.2.1]octane (bridged ketal) ring system. In this paper we present the design, synthesis, preclinical evaluation, and human dose predictions related to 4. This compound demonstrated robust urinary glucose excretion in rats and an excellent preclinical safety profile. It is currently in phase 2 clinical trials and is being evaluated for the treatment of type 2 diabetes.

DIOXA-BICYCLO[3.2.1.]OCTANE-2,3,4-TRIOL DERIVATIVES

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Page/Page column 38-39, (2010/04/06)

Compounds of Formula (I) are described herein and the uses thereof for the treatment of diseases, conditions and/or disorders mediated by sodium-glucose transporter inhibitors (in particular, SGLT2 inhibitors).The compounds disclosed herein are useful for the prevention and treatment of obesity and its associated co-morbidities, inn particular type Il (type 2) diabetes.

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