121042-75-9Relevant academic research and scientific papers
Synthesis of trisaccharide 6' SiaLec and its 6-O-Su derivative
Pazynina, Galina V.,Popova, Inna S.,Belyanchikov, Ivan M.,Tuzikov, Alexander B.,Bovin, Nicolai V.
scheme or table, p. 194 - 195 (2012/10/07)
The synthetic approach to 6'SiaLec and its 6-O-Su derivative comprised α-sialylation of a protected Lec derivative, 2,3-di-OAcGalβ1-3(3-OAc-6-OBn)GlcNAcβ1-Osp (68% yield) as the key stage. Deprotection of the obtained trisaccharide (three stages, 79% overall yield) led to Neu5Acα2-6Galβ1-3GlcNAcβ1-Osp; partial deprotection followed by selective sulfation and total deprotection - to Neu5Acα2-6Galβ1-3(6-O-Su)GlcNAcβ1-Osp (four stages, 72% overall yield).
ARTIFICIAL ANTIGENS AND AFFINITY SORBENTS WITH GROUPS SPECIFICITIES Lea. Leb, and Led
Bovin, N. V.,Zemlyanukhina, T. V.,Chagiashvili, Ts. N.,Khorlin, A. Ya.
, p. 659 - 665 (2007/10/02)
Oligosaccharides of the Lewis system have been synthesized in the form of 3-aminopropylglycosides, from which neoglycoproteins and affinity sorbents have been obtained.All three oligosaccharides were obtained from one and the same precursor.
