1210475-92-5Relevant academic research and scientific papers
Facile approach for the synthesis of 2,3,4,9-tetrahydro-1H-xanthen-1-ones and 8,9,10,12-tetrahydro-11H-benzo[a]xanthen-11-ones via trapping of o-quinone methides
Osyanin, Vitaly A.,Ivleva, Elena A.,Klimochkin, Yuri N.
, p. 1832 - 1847 (2012/04/23)
An efficient, simple synthesis of 2,3,4,9-tetrahydro-1H-xanthene-1-ones and 8,9,10,12-tetrahydro-11H-benzo[a]xanthen-11-ones is reported by one-pot condensation of 3-dimethylamino-2-cyclohexen-1-ones with hydroxybenzyl alcohols, phenol, and 2-naphthol Mannich bases or their quaternized derivatives. The mechanism of the reaction is believed to involve the formation of the o-quinone methide intermediate. Copyright Taylor & Francis Group, LLC.
