121062-96-2Relevant academic research and scientific papers
Antitumor agents. 7. Synthesis and antitumor activity of novel hexacyclic camptothecin analogues
Sugimori,Ejima,Ohsuki,Uoto,Mitsui,Matsumoto,Kawato,Yasuoka,Sato,Tagawa,Terasawa
, p. 3033 - 3039 (2007/10/02)
Eleven novel hexacyclic and three 7,9-disubstituted pentacyclic derivatives of camptothecin were synthesized and evaluated for in vitro cytotoxic activity against P388, HOC-21, and QG-56 and in vivo antileukemic activity against P388 in mice. Hexacyclic c
Hexa-cyclic camptothecin derivatives
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, (2008/06/13)
A novel hexa-cyclic compound, a derivative of camptothecin, of the general formula: STR1 The compound is prepared from an aminoketone compound and a pyranoindolizine compound through Friedlaender reaction. It has an excellent antitumor activity and a high
