121064-15-1

Basic information

• Product Name: 6,7-dimethoxy-1,3,3-trimethyl-3,4-dihydroisoquinoline
• Synonyms: 6,7-dimethoxy-1,3,3-trimethyl-3,4-dihydroisoquinoline
• CAS NO: 121064-15-1
• Molecular Formula: C₁₄H₁₉NO₂
• Molecular Weight: 233.30616
• Mol File: 121064-15-1.mol
• Article Data: 4

Chemical Properties

• Appearance: /
• CAS DataBase Reference: 6,7-dimethoxy-1,3,3-trimethyl-3,4-dihydroisoquinoline(CAS DataBase Reference)
• NIST Chemistry Reference: 6,7-dimethoxy-1,3,3-trimethyl-3,4-dihydroisoquinoline(121064-15-1)
• EPA Substance Registry System: 6,7-dimethoxy-1,3,3-trimethyl-3,4-dihydroisoquinoline(121064-15-1)

Safety Data

• Hazardous Substances Data: 121064-15-1(Hazardous Substances Data)

Upstream product

• 23037-61-8 1-(3,4-dimethoxyphenyl)-2-methylpropan-2-ol 
• 75-05-8 acetonitrile 
• 91-16-7 1,2-dimethoxybenzene 
• 78-84-2 isobutyraldehyde 
• 289054-98-4 (6,7-dimethoxy-3,3-dimethyl-1,2,3,4-tetrahydro-isoquinolylidene)acetic acid ethyl ester 

Downstream Products

• 121064-20-8 6,7-Dimethoxy-1,2,3,3-tetramethyl-3,4-dihydro-isoquinolinium; iodide 
• 1123310-38-2 5,5-dimethyl-8,9-dimethoxy-3-oxo-2,3,5,6-tetrahydropyrrolo[2,1-a]isoquinoline-2-spiro-2'-(3-benzoyl-4-hydroxy-5-oxo-1-phenyl-2,5-dihydro-1H-pyrrole) 
• 1377181-67-3 N-[1-(4-bromophenyl)-2-(6,7-dimethoxy-3,3-dimethyl-3,4-dihydroisoquinolin-1-yl)ethyl]aniline 
• 1377181-91-3 C₆H₃N₃O₇*C₂₇H₂₉ClN₂O₂ 
• 1377181-66-2 N-[1-(4-chlorophenyl)-2-(6,7-dimethoxy-3,3-dimethyl-3,4-dihydroisoquinolin-1-yl)ethyl]aniline 
• 1377181-90-2 C₆H₃N₃O₇*C₂₇H₃₀N₂O₂ 
• 1377181-65-1 N-[2-(6,7-dimethoxy-3,3-dimethyl-3,4-dihydroisoquinolin-1-yl)-1-phenylethyl]aniline 
• 1377181-68-4 N-[2-(6,7-dimethoxy-3,3-dimethyl-3,4-dihydroisoquinolin-1-yl)-1-(2-thienyl)ethyl]aniline 
• 1193109-54-4 (2Z,5Z)-3-hydroxy-5-[3,3-dimethyl-6,7-dimethoxy-3,4-dihydroisoquinolin-1(2H)-ylidene]-1-(4-nitrophenyl)pent-2-ene-1,4-dione 
• 163769-88-8 5,5-dimethyl-2,3,5,6-tetrahydro-(3,4-dimethoxybenzo)quinoxalino<2,3-b>indolizine 

Relevant articles and documents

A new approach to synthesis of 3,3-dialkyl-3,4-dihydroisoquinoline derivatives

The synthesis of 3,3-dialkyl-3,4-dihydroisoquinolines via heterocyclization in three-component reaction of an activated arene with isobutyraldehyde and nitriles is described.

Oxiranes in the Ritter reaction. Synthesis of 6,7- and 5,8-dimethoxy-3,3-dialkyl-3,4-dihydroisoquinolines by a tandem alkylation-cyclization reaction

The interaction of 1,2- or 1,4-dimethoxybenzene with isobutylene oxide and nitriles RCN leads to 1-R-6,7- or 1-R-5,8-dimethoxy-3,3-dimethyl-3,4-dihydroisoquinolines. In the case of 1,2-dimethoxybenzene and cyclohexene oxide the similar reaction is accompa