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1210745-11-1

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1210745-11-1 Usage

Check Digit Verification of cas no

The CAS Registry Mumber 1210745-11-1 includes 10 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 7 digits, 1,2,1,0,7,4 and 5 respectively; the second part has 2 digits, 1 and 1 respectively.
Calculate Digit Verification of CAS Registry Number 1210745-11:
(9*1)+(8*2)+(7*1)+(6*0)+(5*7)+(4*4)+(3*5)+(2*1)+(1*1)=101
101 % 10 = 1
So 1210745-11-1 is a valid CAS Registry Number.

1210745-11-1Downstream Products

1210745-11-1Relevant articles and documents

Toward biophysical probes for the 5-HT3 receptor: Structure-activity relationship study of granisetron derivatives

Vernekar, Sanjeev Kumar V.,Hallaq, Hasan Y.,Clarkson, Guy,Thompson, Andrew J.,Silvestr, Linda,Lummis, Sarah C. R.,Lochner, Martin

supporting information; experimental part, p. 2324 - 2328 (2010/07/17)

This report describes the synthesis and biological characterization of novel granisetron derivatives that are antagonists of the human serotonin (5-HT3A) receptor. Some of these substituted granisetron derivatives showed low nanomolar binding affinity and allowed the identification of positions on the granisetron core that might be used as attachment points for biophysical tags. A BODIPY fluorophore was appended to one such position and specifically bound to 5-HT3A receptors in mammalian cells.

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