121082-79-9Relevant academic research and scientific papers
A Phosphonium Ylide as a Ligand for [3 + 2] Coupling Reactions of Epoxides with Heterocumulenes under Mild Conditions
Hashimoto, Kousuke,Mori, Yoko,Suga, Hiroyuki,Toda, Yasunori
, p. 10980 - 10987 (2020/09/23)
The potential of carbonyl-stabilized phosphonium ylides as ligands for novel catalysis was explored. We found that the combination of phosphonium ylides and metal halide salts efficiently catalyzed the reaction of epoxides with carbon dioxide under mild c
Tetraarylphosphonium Salt-Catalyzed Synthesis of Oxazolidinones from Isocyanates and Epoxides
Toda, Yasunori,Gomyou, Shuto,Tanaka, Shoya,Komiyama, Yutaka,Kikuchi, Ayaka,Suga, Hiroyuki
supporting information, p. 5786 - 5789 (2017/11/10)
Preparation of a range of oxazolidinones, including enantioenriched N-aryl-substituted oxazolidinones, in which tetraarylphosphonium salts (TAPS) catalyze the [3 + 2] coupling reaction of isocyanates and epoxides effectively, is described. The key finding is a Br?nsted acid/halide ion bifunctional catalyst that can accelerate epoxide ring opening with high regioselectivity. Mechanistic studies disclosed that the ylide generated from TAPS, along with the formation of halohydrins, plays a crucial role in the reaction with isocyanates.
Isocyanurate Formation During Oxazolidinone Synthesis from Epoxides and Isocyanates Catalysed by a Chromium(Salphen) Complex
Wu, Xiao,Mason, Jess,North, Michael
, p. 12937 - 12943 (2017/09/25)
Chromium(salphen) complex 10 is found to be a catalyst for the preparation of oxazolidinones from epoxides and isocyanates. Using the optimal reaction conditions (1.5 mol % of chromium(salphen) complex 10 at 80 °C in toluene for 4 hours), six epoxides wer
Synthesis of Oxazolidinones from Epoxides and Isocyanates Catalysed by Aluminium Heteroscorpionate Complexes
Castro-Osma, José A.,Earlam, Amy,Lara-Sánchez, Agustín,Otero, Antonio,North, Michael
, p. 2100 - 2108 (2016/07/07)
The combination of an aluminium(heteroscorpionate) complex and tetrabutylammonium bromide acts as a highly efficient catalyst system for the synthesis of oxazolidinones from epoxides and isocyanates. Twenty two complexes were tested derived from a range o
VanadiumV(salen) catalysed synthesis of oxazolidinones from epoxides and isocyanates
Beattie, Christopher,North, Michael
, p. 31345 - 31352 (2014/08/05)
The combination of a vanadiumV(salen) complex V +O(salen) EtOSO3- and tetrabutylammonium bromide forms a highly active catalyst system for the reaction between epoxides and isocyanates leading to oxazolidinones.
Bimetallic aluminum(salen) catalyzed synthesis of oxazolidinones from epoxides and isocyanates
Baronsky, Thilo,Beattie, Christopher,Harrington, Ross W.,Irfan, Reyhan,North, Michael,Osende, Javier G.,Young, Carl
, p. 790 - 797 (2013/06/27)
The bimetallic aluminum(salen) complex [Al(salen)]2O is shown to catalyze the synthesis of oxazolidinones from epoxides and isocyanates. The reaction is demonstrated to proceed with overall retention of epoxide stereochemistry, and both aromati
OXAZOLIDINONES
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, (2008/06/13)
Novel oxazolidinones of the formula I STR1 Z is O or S, R. sup.1 and R 2 are each phenyl or benzyl radicals which are unsubstituted or mono-or disubstituted by alkyl, alkoxy, alkylthio, alkylsulfinyl and/or alkylsulfonyl having each 1-4 C atoms, alkanoylo
Model Studies for the Mechanism of Inactivation of Monoamine Oxidase by 5-(Aminomethyl)-3-aryl-2-oxazolidinones
Gates, Kent S.,Silverman, Richard B.
, p. 8891 - 8895 (2007/10/02)
3-phenyl>-5--2-oxazolidinone (MD 780236) has been reported to be an irreversible inactivator of monoamine oxidase (MAO), but the mechanism of inactivation is not known.A mechanism is now proposed that invol
