121086-97-3

Basic information

• Product Name: 1-(3-azido-2,3-dideoxy-beta-D-erythro-pentofuranosyl)-5-methylpyrimidin-2(1H)-one
• Synonyms: 1-(3-Azido-2,3-dideoxy-.beta.-D-erythropentofuranosyl)-5-methyl-2(1H)-pyrimidinone; 1-(3-Azido-2,3-dideoxy-beta-D-erythropentofuranosyl)-5-methyl-2(1H)-pyrimidinone; 2(1H)-Pyrimidinone, 1-(3-azido-2,3-dideoxy-b-D-erythro-pentofuranosyl)-5-methyl-; 2(1H)-Pyrimidinone, 1-(3-azido-2,3-dideoxy-beta-D-erythro-pentofuranosyl)-5-methyl-
• CAS NO: 121086-97-3
• Molecular Formula: C₁₀H₁₃N₅O₃
• Molecular Weight: 251.2419
• Mol File: 121086-97-3.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: 1-(3-azido-2,3-dideoxy-beta-D-erythro-pentofuranosyl)-5-methylpyrimidin-2(1H)-one(CAS DataBase Reference)
• NIST Chemistry Reference: 1-(3-azido-2,3-dideoxy-beta-D-erythro-pentofuranosyl)-5-methylpyrimidin-2(1H)-one(121086-97-3)
• EPA Substance Registry System: 1-(3-azido-2,3-dideoxy-beta-D-erythro-pentofuranosyl)-5-methylpyrimidin-2(1H)-one(121086-97-3)

Safety Data

• Hazardous Substances Data: 121086-97-3(Hazardous Substances Data)

Upstream product

• 87190-77-0 1-(5-O-Acetyl-3-azido-2,3-dideoxy-β-D-erythro-pentofuranosyl)-5-methyl-4-(1,2,4-triazol-1-yl)-2(1H)-pyrimidinone 

Relevant articles and documents

Nucleoside and use thereof

A compound 1-(3-azido-2,3-dideoxy-β-D-erythro-pentofuranoxyl)-5-methyl-2(1H)-pyrimidinone and its use in a method of generating (forming, providing) 3'-azido-3'-deoxythymidine (zidovudine sometimes referred to as AZT) in the body of an animal (a mammal such as human) by systemically administering 1-(3-azido-2,3-dideoxy-β-D-erythro-pentofuranosyl)-5-methyl-2(1H)-pyriminone to said animal (mammal such as a human) is disclosed. AZT is approved and used for treating HIV infections, e.g., AIDS and ARC in humans and also has activity against gram-negative bacteria in animals.