121088-09-3 Usage
General Description
1,4-Bis(tert-butoxy)tetrafluorobenzene is a chemical compound with the molecular formula C16H20F4O2. It is a colorless, odorless liquid that is insoluble in water. This chemical is commonly used as a solvent in various industrial processes, as well as a reagent in organic synthesis. It is also utilized in the production of pharmaceuticals, agrochemicals, and specialty chemicals. Additionally, 1,4-Bis(tert-butoxy)tetrafluorobenzene is known for its high thermal stability and resistance to chemical reactions, making it a valuable component in the manufacturing of advanced materials and coatings. However, it is important to handle this compound with care, as it may pose health and environmental risks if not properly managed.
Check Digit Verification of cas no
The CAS Registry Mumber 121088-09-3 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 1,2,1,0,8 and 8 respectively; the second part has 2 digits, 0 and 9 respectively.
Calculate Digit Verification of CAS Registry Number 121088-09:
(8*1)+(7*2)+(6*1)+(5*0)+(4*8)+(3*8)+(2*0)+(1*9)=93
93 % 10 = 3
So 121088-09-3 is a valid CAS Registry Number.
InChI:InChI=1/C14H18F4O2/c1-13(2,3)19-11-7(15)9(17)12(10(18)8(11)16)20-14(4,5)6/h1-6H3
121088-09-3Relevant articles and documents
Mechanism and Scope of Base-Controlled Catalyst-Free N-Arylation of Amines with Unactivated Fluorobenzenes
Borch Jacobsen, Christian,Meldal, Morten,Diness, Frederik
, p. 846 - 851 (2017/02/05)
A general method for transition metal-free N-arylation of amines has been developed. Mechanistic studies have revealed that the ability of the base to facilitate the desired amination without promoting unwanted side reactions is the guiding factor. By employing lithium bis(trimethylsilyl)amide as a base the resultant deprotonated amines readily react with a range of unactivated fluorobenzene derivatives. This new arylation method is utilized for the simple two-step synthesis of the antidepressant Vortioxetine.
Polyhalogenoaromatic Compounds. Part 53. Substitution in Polyfluoroaromatic Compounds by Bulky Nucleophiles
Cheong, Catherine L.,Wakefield, Basil J.
, p. 3301 - 3306 (2007/10/02)
Potassium t-butoxide in THF is highly reactive towards polyfluoroaromatic compounds.The position(s) of substitution are generally similar to those observed with other nucleophiles, though octafluoronaphthalene undergoes ca. 30percent 2,7-disubstitution.He
