121105-86-0

Basic information

• Product Name: 2-benzyl-1-chloro-3-methylbenzo[4,5]imidazo[1,2-a]pyridine-4-carbonitrile
• Synonyms: 2-benzyl-1-chloro-3-methylbenzo[4,5]imidazo[1,2-a]pyridine-4-carbonitrile
• CAS NO: 121105-86-0
• Molecular Formula: C₂₀H₁₄ClN₃
• Molecular Weight: 331.79826
• Mol File: 121105-86-0.mol
• Article Data: 4

Chemical Properties

• Melting Point: 220-223 °C(Solv: N,N-dimethylformamide (68-12-2); water (7732-18-5))
• Appearance: /
• Density: 1.27±0.1 g/cm3(Predicted)
• PKA: 2.18±0.50(Predicted)
• CAS DataBase Reference: 2-benzyl-1-chloro-3-methylbenzo[4,5]imidazo[1,2-a]pyridine-4-carbonitrile(CAS DataBase Reference)
• NIST Chemistry Reference: 2-benzyl-1-chloro-3-methylbenzo[4,5]imidazo[1,2-a]pyridine-4-carbonitrile(121105-86-0)
• EPA Substance Registry System: 2-benzyl-1-chloro-3-methylbenzo[4,5]imidazo[1,2-a]pyridine-4-carbonitrile(121105-86-0)

Safety Data

• Hazardous Substances Data: 121105-86-0(Hazardous Substances Data)

Upstream product

• 4414-88-4 1H-benzimidazol-2-acetonitrile 
• 620-79-1 Ethyl 2-benzylacetoacetate 
• 100-39-0 benzyl bromide 
• 121105-74-6 2-benzyl-3-methyl-1-oxo-1H,5H-pyrido<1,2-a>benzimidazole-4-carbonitrile 

Downstream Products

• 305334-34-3 2-benzyl-1-(cyclohexylamino)-3-methylbenzo[4,5]imidazo[1,2-a]pyridine-4-carbonitrile 
• 305332-74-5 2-benzyl-3-methyl-1-(p-tolylamino)benzo[4,5]imidazo[1,2-a]pyridine-4-carbonitrile 

Relevant articles and documents

Synthesis of a Novel Library of 1-Substituted Pyrido[1,2- a ]benzimidazoles

The reactivity and synthesis of new analogues of pyrido[1,2-a]benzimidazoles have been explored. Twenty-three derivatives bearing phenoxy, thiophenoxy, aniline, and aryl groups at the 1-position were successfully synthesised in 25-91 % yield, via nucleoph

IMIDAZO(1,2-a)PYRIDINE DERIVATIVE

A compound reprsented by the following formula (I), its salts or nsolvates thereof capable of specifically or selectively expressig an antifungal activity in a broad spectrum based on the novel mechanism thereof of 1,6-β-glucan synthesis inhibition, and an antifungal agent containing any of them.