[2-chloro-5-(3,3-diethoxy-prop-1-ynyl)-pyrimidin-4-yl]-cyclopentyl amine, also known as CEP-1347, is a chemical compound that functions as a potent and selective inhibitor of the neurotrophin receptor TrkA. It is characterized by its ability to protect neurons from apoptosis, promote neuronal survival, and exhibit anti-inflammatory properties.
1211442-87-3
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Basic information
- Product Name: [2-chloro-5-(3,3-diethoxy-prop-1-ynyl)-pyrimidin-4-yl]-cyclopentyl amine
- Synonyms:
- CAS NO:1211442-87-3
- Molecular Formula:
- Molecular Weight: 323.823
- EINECS: N/A
- Product Categories: N/A
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Chemical Properties
- Melting Point: N/A
- Boiling Point: 481.5±45.0 °C(Predicted)
- Flash Point: N/A
- Appearance: N/A
- Density: 1.20±0.1 g/cm3(Predicted)
- Refractive Index: N/A
- Storage Temp.: N/A
- Solubility: N/A
- CAS DataBase Reference: [2-chloro-5-(3,3-diethoxy-prop-1-ynyl)-pyrimidin-4-yl]-cyclopentyl amine(CAS DataBase Reference)
- NIST Chemistry Reference: [2-chloro-5-(3,3-diethoxy-prop-1-ynyl)-pyrimidin-4-yl]-cyclopentyl amine(1211442-87-3)
- EPA Substance Registry System: [2-chloro-5-(3,3-diethoxy-prop-1-ynyl)-pyrimidin-4-yl]-cyclopentyl amine(1211442-87-3)
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Safety Data
- Hazard Codes: N/A
- Statements: N/A
- Safety Statements: N/A
- WGK Germany:
- RTECS:
- HazardClass: N/A
- PackingGroup: N/A
- Hazardous Substances Data: 1211442-87-3(Hazardous Substances Data)
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1211442-87-3 Usage
Uses
Used in Pharmaceutical Industry:CEP-1347 is used as a therapeutic agent for neurodegenerative diseases such as Alzheimer's disease and Parkinson's disease. It is utilized for its neuroprotective properties, which involve blocking the signaling pathways that lead to cell death and promoting neuronal survival.
Used in Immunology Research:
CEP-1347 is used as an anti-inflammatory agent in the study and treatment of immune-related diseases. Its anti-inflammatory properties make it a potential candidate for managing conditions involving inflammation.
Used in Oncology Research:
CEP-1347 is used as a potential anti-cancer agent due to its ability to inhibit tumor growth and promote apoptosis in cancer cells. It is investigated for its potential to modulate oncological signaling pathways and enhance the efficacy of conventional chemotherapeutic drugs, particularly in resistant cases.
Check Digit Verification of cas no
The CAS Registry Mumber 1211442-87-3 includes 10 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 7 digits, 1,2,1,1,4,4 and 2 respectively; the second part has 2 digits, 8 and 7 respectively.Calculate Digit Verification of CAS Registry Number 1211442-87:
(9*1)+(8*2)+(7*1)+(6*1)+(5*4)+(4*4)+(3*2)+(2*8)+(1*7)=103
103 % 10 = 3
So 1211442-87-3 is a valid CAS Registry Number.
1211442-87-3Upstream product
1211442-87-3Downstream Products
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[2-chloro-5-(3,3-diethoxy-prop-1-ynyl)-pyrimidin-4-yl]-cyclopentyl amine
