121145-33-3Relevant articles and documents
ASYMMETRIC ELECTROPHILIC α-AMIDOALKYLATION 5: IMPROVED STEREOSELECTIVITIES THROUGH NEW CHIRAL AUXILIARIES
Wanner, Klaus Th.,Kaertner, Annerose,Wadenstorfer, Elmar
, p. 2549 - 2556 (2007/10/02)
Enamides of type 2 were employed in asymmetric α-amidoalkylation reactions with silyl enol ether 4 as nucleophile.Depending on the chiral auxiliary used, (R)-5/(S)-5 stereoselectivities up to 95/5 could be reached.Based on the obtained results a model for