1211517-76-8

Basic information

• Product Name: 3-BroMo-5fluoro-4-Methylpyridine
• Synonyms: 3-BroMo-5fluoro-4-Methylpyridine
• CAS NO: 1211517-76-8
• Molecular Formula: C6H5BrFN
• Molecular Weight: 190.0130032
• Mol File: 1211517-76-8.mol
• Article Data: 7

Chemical Properties

• Boiling Point: 183.5±35.0 °C(Predicted)
• Appearance: /
• Density: 1.592±0.06 g/cm3(Predicted)
• Storage Temp.: under inert gas (nitrogen or Argon) at 2-8°C
• PKA: 1.11±0.28(Predicted)
• CAS DataBase Reference: 3-BroMo-5fluoro-4-Methylpyridine(CAS DataBase Reference)
• NIST Chemistry Reference: 3-BroMo-5fluoro-4-Methylpyridine(1211517-76-8)
• EPA Substance Registry System: 3-BroMo-5fluoro-4-Methylpyridine(1211517-76-8)

Safety Data

• Hazardous Substances Data: 1211517-76-8(Hazardous Substances Data)

Usage

General Description

3-Bromo-5-fluoro-4-methylpyridine is a chemical compound with the molecular formula C6H5BrFN. It is a pyridine derivative with bromine, fluorine, and methyl substituents. 3-BroMo-5fluoro-4-Methylpyridine is commonly used in organic chemistry as a building block to create more complex molecules and pharmaceutical compounds. It is also used as an intermediate in the synthesis of agrochemicals and pharmaceuticals. 3-Bromo-5-fluoro-4-methylpyridine may also have potential applications in the field of medicinal chemistry and drug discovery due to its unique structural properties. However, it is important to handle this chemical with care as it may pose health and safety hazards if not used properly.

Upstream product

• 407-20-5 3-bromo-5-fluoropyridine 
• 74-88-4 methyl iodide 

Downstream Products

• 1431937-73-3 4-bromo-2-((5-fluoro-4-methylpyridin-3-yl)ethynyl)aniline 

Relevant articles and documents

ALDOSTERONE SYNTHASE INHIBITORS

The present invention relates to compounds of formula I: and pharmaceutically acceptable salts thereof, wherein R1, R2 and R3, are as defined herein. The invention also relates to pharmaceutical compositions comprising these compounds, methods of using these compounds in the treatment of various diseases and disorders, processes for preparing these compounds and intermediates useful in these processes.

Discovery of benzimidazole CYP11B2 inhibitors with in vivo activity in rhesus monkeys

We report the discovery of a benzimidazole series of CYP11B2 inhibitors. Hit-to-lead and lead optimization studies identified compounds such as 32, which displays potent CYP11B2 inhibition, high selectivity versus related CYP targets, and good pharmacokin

TRIAZOLOPYRIDYL COMPOUNDS AS ALDOSTERONE SYNTHASE INHIBITORS

This invention relates to triazolopyridyl compounds of the structural formula: [Formula should be inserted here] or their pharmaceutically acceptable salts, wherein the variable are defined herein. The inventive compounds selectively inhibit aldosterone synthase. This invention also provides for pharmaceutical compositions comprising the compounds of Formula I or their salts as well as potentially to methods for the treatment, amelioration or prevention of conditions that could be treated by inhibiting aldosterone synthase.