1211538-23-6Relevant articles and documents
Discovery of potent dipeptidyl peptidase IV inhibitors derived from β-aminoamides bearing substituted [1,2,3]-triazolopiperidines for the treatment of type 2 diabetes
Shan, Zhenwei,Peng, Min,Fan, Houxing,Lu, Qingtao,Lu, Peng,Zhao, Chuansheng,Chen, Yilang
scheme or table, p. 1731 - 1735 (2011/05/05)
A series of novel [1,2,3]-triazolopiperidine derivatives 5a-5y were synthesized and evaluated as inhibitors of dipeptidyl peptidase IV (DPP-4) for the treatment of type 2 diabetes, most of the compounds exhibited excellent in vitro potency (IC50/sub