1211540-79-2

Basic information

• Product Name: 1H-Pyrrolo[3,2-b]pyridine, 2,3-dihydro-
• Synonyms: 1H-Pyrrolo[3,2-b]pyridine, 2,3-dihydro-;2,3-Dihydro-1H-pyrrolo[3,2-b]pyridine;1H,2H,3H-Pyrrolo[3,2-b]pyridine
• CAS NO: 1211540-79-2
• Molecular Formula: C₇H₈N₂
• Molecular Weight: 120.15182
• Mol File: 1211540-79-2.mol
• Article Data: 7

Chemical Properties

• Boiling Point: 243.7±9.0 °C(Predicted)
• Appearance: /
• Density: 1.114±0.06 g/cm3(Predicted)
• Storage Temp.: Keep in dark place,Inert atmosphere,Room temperature
• PKA: 7.18±0.20(Predicted)
• CAS DataBase Reference: 1H-Pyrrolo[3,2-b]pyridine, 2,3-dihydro-(CAS DataBase Reference)
• NIST Chemistry Reference: 1H-Pyrrolo[3,2-b]pyridine, 2,3-dihydro-(1211540-79-2)
• EPA Substance Registry System: 1H-Pyrrolo[3,2-b]pyridine, 2,3-dihydro-(1211540-79-2)

Safety Data

• Hazardous Substances Data: 1211540-79-2(Hazardous Substances Data)

Usage

General Description

1H-Pyrrolo[3,2-b]pyridine, 2,3-dihydro- is a chemical compound with a molecular formula C9H8N2. It is a bicyclic heteroaromatic compound that contains a pyrrolopyridine ring system. 1H-Pyrrolo[3,2-b]pyridine, 2,3-dihydro- is used in medicinal chemistry and pharmaceutical research as a building block for the synthesis of various biologically active molecules. It has been studied for its potential use in the development of new drugs and has shown promising properties in preclinical studies. Additionally, 1H-Pyrrolo[3,2-b]pyridine, 2,3-dihydro- has been investigated for its potential application as a fluorescent probe in analytical chemistry and bioimaging.

Upstream product

• 272-49-1 1H-pyrrolo[3,2-b]pyridine 
• 5470-18-8 2-Chloro-3-nitropyridine 
• 178896-74-7 ethyl (3-nitropyridin-2-yl)acetate hydrochloride 
• 918153-29-4 2-(3-aminopyridin-2-yl)ethanol 
• 1260802-19-4 tert-butyl [2-(2-hydroxyethyl)pyridin-3-yl]carbamate 
• 1338219-71-8 2-{3-[(tert-butoxycarbonyl)amino]pyridin-2-yl}ethyl methanesulfonate 
• 1254360-67-2 tert-butyl 2,3-dihydro-1H-pyrrolo[3,2-b]pyridine-1-carboxylate 
• 295327-27-4 ethyl 2-(3-amino-pyridin-2-yl)-acetate 
• 1018950-15-6 1H-pyrrolo[3,2-b]pyridine-1-carboxylic acid 1,1-dimethylethyl ester 
• 1443981-64-3 2,3-dihydro-1H-pyrrolo[3,2-b]pyridine hydrochloride 

Downstream Products

• 1260671-35-9 5-bromo-2,3-dihydro-1H-pyrrolo[3,2-b]pyridine 

Relevant articles and documents

NOVEL SUBSTITUTED TETRAHYDROQUINOLIN COMPOUNDS AS INDOLEAMINE 2,3-DIOXYGENASE (IDO) INHIBITORS

Disclosed herein is a compound of formula (I), or a pharmaceutically acceptable salt thereof (I). Also disclosed herein are uses of the compounds disclosed herein in the potential treatment or prevention of an IDO-associated disease or disorder. Also disclosed herein are compositions comprising a compound disclosed herein. Further disclosed herein are uses of the compositions in the potential treatment or prevention of an IDO-associated disease or disorder.

This new pharmaceutical use (6-1, 6-dihydro-2-yl) amide derivative, as the inhibitor of this preparation and AKT (PKB) phosphoenzyme

The invention relates to the novel materials of formula (I), wherein each of the substituents R, R1, R2, R3, R4 and R5 is as defined herein. The materials are useful as inhibitors of AKT(PKB) phosphorylation.

Preparation of azaindolines and benzoyl substituted azaindolines: Precursors of triazabenzo[cd]azulen-9-one PDE4 inhibitors

The syntheses of various substituted azaindolines are described. Azaindolines were identified as potential key intermediates towards new PDE4 inhibitors.